For US Healthcare Professionals

Updated Guidance: VYJUVEK is now approved for use from birth, can be applied by a caregiver or patient at-home, has an increased weekly volume, & has the flexibility of being removed at your next dressing change.

VYJUVEK At-Home Application Personalized for Your Patient

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Krystal Connect is a personalized patient support program

The first step to getting your patients started on VYJUVEK via Krystal Connect is to download and fill out the Krystal Connect Enrollment Form.

Download Form
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Educating patients about VYJUVEK and living with DEB

  • Providing disease education and resources on DEB
  • Webinars, emails, and programs that share real-world experience from those on VYJUVEK
  • Connection to additional resources for the DEB community through advocacy groups
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Providing insurance coverage support

  • Assist with the insurance process, including benefits investigation and prior authorizations
  • The VYJUVEK Quick Start Program provides a temporary supply of medication at no cost to patients prescribed VYJUVEK while the insurance approval is in process for eligible patients
  • Inform patients about potential financial assistance options and eligibility requirements as needed
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Supporting routine wound care

  • VYJUVEK can be applied in your patient’s home or at a healthcare setting
    • >95% of patients have VYJUVEK applied weekly at their home
  • Education and personalized support on cleansing, ointments, and hydrophobic dressings to ensure proper application of VYJUVEK

To contact Krystal Connect, please call 1-844-5-KRYSTAL or use our Connect With Us form.

Krystal Biotech has partnered with Option Care Health®, a national pharmacy and in-home nursing service.

  • Your patient's Krystal Connect™ Patient Access Liaison (PAL) will work with Option Care Health to guide your patient through each step of the process
  • Option Care Health will obtain insurance authorization and coordinate deliveries of VYJUVEK to your patient's home and provide support to your patients as needed
  • Clinical Nurse Educators provide application training for patients and caregivers who will apply VYJUVEK, allowing them to personalize how application will fit into their current routine
  • Option Care Health provides all auxiliary supplies needed for treatment with VYJUVEK including gloves, scissors, and the hydrophobic dressings to be applied after administration. They also provide a sharps container for disposal of used supplies
  • Your patient's Krystal Connect™ Patient Access Liaison (PAL) will work with Option Care Health to guide your patient through each step of the process
  • Option Care Health will obtain insurance authorization and coordinate deliveries of VYJUVEK to your patient's home and provide support to your patients as needed
  • Clinical Nurse Educators provide application training for patients and caregivers who will apply VYJUVEK, allowing them to personalize how application will fit into their current routine
  • Option Care Health provides all auxiliary supplies needed for treatment with VYJUVEK including gloves, scissors, and the hydrophobic dressings to be applied after administration. They also provide a sharps container for disposal of used supplies

View Additional Helpful Forms and Resources

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INDICATION AND USAGE

VYJUVEK is a topical gel indicated for the treatment of wounds in adult and pediatric patients (from birth) with dystrophic epidermolysis bullosa (DEB) with mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Accidental Exposure to VYJUVEK gel: VYJUVEK will not replicate in the subject’s cells and does not integrate into the subject cells’ native genetic material. For precautions, avoid direct contact with treated wounds (e.g., touching or scratching) and dressings of treated wounds until the next dressing change following treatment. Wear protective gloves when assisting patients with changing wound dressings and handling the disposal. In the event of accidental exposure (e.g., through a splash to the eyes or mucous membranes), flush with clean water for at least 15 minutes.

Clean all surfaces that may have come in contact with VYJUVEK biological suspension or gel and treat all spills with a virucidal agent.

Dispose all materials (e.g., vial, syringe, cleaning materials) that may have come in contact with VYJUVEK biological suspension or gel into a biohazard container.

ADVERSE REACTIONS

The most common adverse reactions (>5%) were itching, chills, redness, rash, cough, and runny nose.


  • Please see Important Safety Information above and click here for full Prescribing Information.
IMPORTANT SAFETY INFORMATION
INDICATION AND USAGE

VYJUVEK is a topical gel indicated for the treatment of wounds in adult and pediatric patients (from birth) with dystrophic epidermolysis bullosa (DEB) with mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Accidental Exposure to VYJUVEK gel: VYJUVEK will not replicate in the subject’s cells and does not integrate into the subject cells’ native genetic material. For precautions, avoid direct contact with treated wounds (e.g., touching or scratching) and dressings of treated wounds until the next dressing change following treatment. Wear protective gloves when assisting patients with changing wound dressings and handling the disposal. In the event of accidental exposure (e.g., through a splash to the eyes or mucous membranes), flush with clean water for at least 15 minutes.

Clean all surfaces that may have come in contact with VYJUVEK biological suspension or gel and treat all spills with a virucidal agent.

Dispose all materials (e.g., vial, syringe, cleaning materials) that may have come in contact with VYJUVEK biological suspension or gel into a biohazard container.

ADVERSE REACTIONS

The most common adverse reactions (>5%) were itching, chills, redness, rash, cough, and runny nose.


  • Please see Important Safety Information above and click here for full Prescribing Information.